Analysis of three common mutations that cause early-onset autosomal recessive Parkinson’s disease

Takeaway

  • In a large cohort of autosomal recessive Parkinson’s disease cases, type of genetic mutation influences phenotypic characteristics such as age at onset and disease presentation.

Why this matters

    These findings could have a significant impact on who is selected for genetic testing, based on age at onset, pattern of disease presentation, and ethnicity.