Cerebrospinal Fluid Neurofilament Light Protein Associated with Risk of Mild Cognitive Impairment

Takeaway

  • Cerebrospinal fluid (CSF) neurofilament light protein (NfL) could be a valuable biomarker of early neurodegeneration but is not specific to the pathobiology of Alzheimer’s disease (AD).

Why this matters

  • Previous work has not investigated CSF markers in the community or investigated them in relation to mild cognitive impairment.