Imaging sheds light on impact of white matter injury on brain structure and function in very preterm neonates

Takeaway

  • In very preterm neonates, white matter injury (WMI) has a greater impact on functional connectivity than on microstructural connectivity, and spatial extent of injury is not predictive of changes.

Why this matters

  • Large lesions in one white matter pathway may have less impact on brain structure and function than small lesions in multiple pathways.