New findings help explain sex differences in glioblastoma

Specialists have reported that metabolic analyses reveal significant differences between glioblastoma cells from men and women, that may help account for sex differences in incidence and survival.

Glioblastoma is more common in males than in females, and female patients tend to survive significantly longer than male patients. The higher incidence in males has also been observed in other mammals, including dogs. Understanding the reasons for these sex differences could support the development of novel therapies and treatment strategies.