Osteoporosis and cerebral small vessel disease

Takeaway

  • It is possible that a mechanistic association exists between loss of bone mineral density (BMD) and cerebral small vessel disease (SVD).

Why this matters

    The pathophysiology of cerebral SVD remains incompletely explained by traditional risk factors, such as hypertension and dyslipidemia. A recent study suggested that vascular dysfunction could be independently related to osteoporosis; however, detailed data is lacking.