Predicting conversion from clinically isolated syndrome to multiple sclerosis

Takeaway

  • Brain images from people with clinically isolated syndrome (CIS) can be automatically segmented and analysed to predict potential conversion of CIS to multiple sclerosis (MS).

Why this matters

  • CIS is characterized as an episode of neurological symptoms that is indicative of an inflammatory demyelinating disease of the CNS, and while its occurrence may be a risk factor for developing MS, not all patients undergo conversion.