Predictors of long-term motor response to bilateral subthalamic nucleus deep brain stimulation

Takeaway

  • In people with Parkinson’s disease (PD), better long-term motor response to bilateral subthalamic nucleus deep brain stimulation (STN-DBS) is predicted by dysfunction in the frontal lobe and worse disease severity off-medication, with worse long-term motor response in those with vascular changes on magnetic resonance imaging (MRI).

Why this matters

    This study indicates that screening for executive functions and brain MRI imaging may help identify appropriate candidates for long-term response to STN-DBS surgery.