Predictors of seizure outcomes after magnetic resonance-guided laser interstitial thermal therapy

Takeaway

  • Age at surgery and presence of bilateral interictal epileptiform discharges (IEDs) are factors associated with 1-year seizure outcome after magnetic resonance-guided laser interstitial thermal therapy (MRgLiTT) of unilateral mesial temporal sclerosis (MTS) in patients with mesial temporal lobe epilepsy (mTLE).

Why this matters

  • MRgLiTT is a minimally invasive treatment option for mTLE, but at least one third of patients experience early seizure recurrence after surgery.

  • Identification of baseline factors that are associated with outcome of MRgLiTT is crucial in determining patients who may benefit from the surgery, and in understanding reasons for surgical failure and deciding further surgical options.