Tau368: a novel cerebrospinal fluid biomarker in Alzheimer’s disease ?

Takeaway

  • Tau368 is a novel biomarker of tau pathology and could be used in the future for diagnosis of Alzheimer’s disease (AD) or development of tau-targeting drugs.

Why this matters

  • Tau protein tangles are a key pathological element of Alzheimer’s disease (AD), yet there is no validated cerebrospinal fluid (CSF) biomarker to detect tau protein.

  • A fragment of tau called tau368 could be a potential new biomarker.